When opening up slots, I mark out, drill a hole, dremel out to within about 1mm of the slot, then use small files or needle files to finish off, that way you maintain control. If you have a lot of slots to do, and they're of the same or similar size, it's worth considering the use of a pre-made stencil.
A slow and laborious task for a U-boat with it's myriad of drainage slots. Diamond coated needle files are best for glass work I find. They don't blunt out and are a bit coarser than the high carbon steel types.
Andy